POSSIBLE CNS DEPRESSANT EFFECTS OF SOME NEWLY SYNTHESIZED QUINAZOLINONE DERIVATIVES
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چکیده
منابع مشابه
Synthesis of some new tricyclic 4(3H)-quinazolinone derivatives
Quinazolinones are interesting molecules with a wide range of biological activities. We prepared a number of quinazolinone derivatives by the condensation of 5-bromo- or 5-nitro-substituted anthranilic acids with chloro-acyl chlorides. Anthranilic acid derivatives were treated with either 3-chloro-propionyl chloride or 4-chloro-butyryl chloride to yield the corresponding N-acyl-anthranilic acid...
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Quinazolinones are interesting materials because of their valuable biological effects. In this study some new 2,3-disubstituted-4(3H)quinqzolinone derivatives were synthesized from anthranilic acid in six steps by introducing a new chiral center to the aliphatic side chain of the quinazolinone. In the last step, a single acylation on the hydrazine moiety afforded final compounds. The structures...
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ژورنال
عنوان ژورنال: Bulletin of Pharmaceutical Sciences. Assiut
سال: 1990
ISSN: 1110-0052
DOI: 10.21608/bfsa.1990.70558